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Deep endometriosis: surgery vs. IVF in fertility showdown

NCT ID NCT04610710

Disease control Sponsor: Horsens Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early This study
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compared two approaches for women with deep endometriosis who want to get pregnant: surgery to remove endometriosis or fertility treatment (IVF). Researchers planned to track pregnancy and live birth rates. The trial was stopped early after enrolling 38 women, so the results are limited and may not give a clear answer.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors and patients choose the best first step—surgery or IVF—to improve pregnancy chances in deep endometriosis.
What could go wrong
The trial was terminated early with only 38 participants, so results are limited. It may not provide clear answers, and individual outcomes vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

38 people

The number who actually took part.

Started

Nov 2020

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 38 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Rectosigmoid endometriosis and wish for surgery * Pregnancy intention for at least 6 months * AMH above 5 pmol/ml * Maximum of 2 previous IVF treatments * Male partner Exclusion Criteria: * Endometriosis involving the ureter unilaterally or bilaterally (randomization unethical) * BMI above 32 * Contraindication for IVF (untreated uterine factor infertility, untreated/maltreated systemic or malignant disease, oocyte aspiration severely riskful (e.g. severe abdominal adhesions) * No wish for randomization

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Conditions

The condition(s) this trial relates to.

endometriosis endometriosis of intestine female infertility infertility disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Deep endometriosis Infertility, female

Contacts and locations

Locations

  • Aarhus University Hospital

    Aarhus N, Central Region, 8200, Denmark

  • Horsens Regional Hospital

    Horsens, Central Region, 8700, Denmark

  • The Endometriosis Center, Clinique Tivoli-Ducos

    Bordeaux, France

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