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Double attack: surgery plus laser zaps deadly brain tumors

NCT ID NCT07384884

First seen Feb 03, 2026 · Last updated Jun 19, 2026 · Updated 26 times

Summary

This study tests a new approach for a rare and aggressive brain tumor called butterfly glioblastoma, which crosses both sides of the brain and has a very poor outlook. The treatment combines open surgery to remove as much tumor as possible from one side, followed by a minimally invasive laser therapy to destroy the remaining tumor on the other side. The goal is to improve survival and preserve brain function, with 12 participants being closely monitored for cognitive and quality-of-life outcomes.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • King's College NHS Foundation Trust

    London, SE5 9RS, United Kingdom

    Contact Phone: •••-•••-••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

surgery and laser interstitial thermal therapy (LITT)

What this could lead to

If successful, this combined approach could offer a new treatment option for patients with butterfly glioblastoma, potentially extending survival and reducing brain damage compared to current methods.

What could go wrong

This is a very early, small trial with only 12 participants, so results may not apply to all patients. The procedure carries risks like infection, bleeding, or stroke, and the tumor may still progress.

Conditions

The condition(s) this trial relates to.

brain cancer brain neoplasm glioblastoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.