Surgery offers new hope for chronic pain sufferers
NCT ID NCT07263256
First seen Dec 16, 2025 · Last updated Jun 23, 2026 · Updated 35 times
Summary
This study tested surgery to treat Complex Regional Pain Syndrome (CRPS) in the upper limb. 74 adults with CRPS who had not improved with other treatments received either nerve decompression or correction of a specific structural problem. Pain levels were measured before surgery, at 10-12 days, and at three months to see how much and how quickly pain changed.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Hospital Nové Město Na Moravě
Nové Město na Moravě, Czech Republic, 592 31, Czechia
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Surgery (median nerve decompression and lesion-specific correction)
What this could lead to
If successful, this surgical approach could offer a new way to reduce pain for people with Complex Regional Pain Syndrome who haven't improved with other treatments.
What could go wrong
This is a small, completed study without a control group, so results may not apply to everyone. Surgery carries risks like infection or nerve damage, and pain relief may not last.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.