New supplement may ease pain and swelling after wisdom tooth surgery
NCT ID NCT07269171
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether taking a dietary supplement containing trypsin, chymotrypsin, and serratia peptidase can help reduce pain, swelling, and jaw stiffness after having a wisdom tooth removed. About 15 healthy adults aged 18 to 45 will take either standard care or standard care plus the supplement. Researchers will check their healing, pain, and swelling over the first week after surgery.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 15 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Dec 2025
An estimate. Start dates often move.
- Expected to finish
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Mar 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 45 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Having a mandibular third molar with a unilateral or bilateral Class 2, Position A or B impaction according to the Pell and Gregory classification * Being systemically healthy (ASA Class I) * Aged between 18 and 45 years (young adult age group) * Willingness to participate in the study Exclusion Criteria: * Age outside the specified range * Pregnancy * Currently breastfeeding * Presence of infection in the third molar region (e.g., acute pericoronitis) * Presence of cystic or tumoral lesions associated with the impacted third molar * History of allergic reactions * Presence of any systemic disease * Unwillingness to participate in the study * Poor oral hygiene that may negatively affect healing * Smoking or alcohol addiction
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Health Sciences University
Ankara, Turkey (Türkiye)
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