Brain-Boosting tablet workout tested for memory loss
NCT ID NCT07101380
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a tablet-based exercise program called SuperBrain BOOM can improve thinking, memory, and physical function in older adults with mild cognitive impairment (MCI). Forty-five participants aged 50-85 will use the program at home or in a clinic for 12 weeks, while a control group receives usual care. The goal is to see if the program is safe, engaging, and effective at slowing cognitive decline.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- SuperBrain BOOM (tablet-based physical activity program)
- What this could lead to
- If it works, this could offer a simple, home-based exercise program to help slow cognitive decline and improve quality of life for people with mild cognitive impairment.
- What could go wrong
- This is a small, early-stage exploratory study with only 45 participants. The program may not show significant benefits, and results may not apply to everyone with MCI.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 45 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2026
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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50 to 85 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age: Between 50 and 85 years old. 2. Meets all of the core clinical criteria for suspected Mild Cognitive Impairment (MCI) according to the National Institute on Aging-Alzheimer's Association (NIA-AA) guidelines as of the screening date: * Concerns of the participant or caregiver regarding cognitive decline compared to prior functioning. * Impairment in at least one cognitive domain. * Preserved independence in overall daily living activities. * No dementia. 3. Has one or more of the following neuropsychological test results within one year of the screening date, with delayed recall scores in the memory domain below the mean -1.0 standard deviation according to age- and education-adjusted normative data: * Seoul Neuropsychological Screening Battery 2nd Edition (SNSB-II) * Korean version of the Consortium to Establish a Registry for Alzheimer's Disease (CERAD-K) * Literacy Independent Cognitive Assessment (LICA) 4. As of the screening date, has a Korea-Mini Mental State Examination (K-MMSE-2) score that corresponds to at least -1.5 standard deviations below the mean based on age- and education-adjusted normative data. 5. As of the screening date, has a Global Clinical Dementia Rating (CDR) score of 0.5, with a memory score of either 0.5 or 1. 6. Capable of using a tablet or smartphone with training, or has a research partner who can assist with using a tablet or smartphone. 7. Has a caregiver who regularly contacts the participant: -A caregiver who is able to support the participant (monitor compliance and report participant status) and spends at least 8 hours per week with the participant during the trial period. 8. The participant provides written informed consent to participate in the study. Exclusion Criteria: 1. Presence of psychiatric disorders, such as major depression. 2. Dementia. 3. Other neurodegenerative diseases, such as Parkinson's disease. 4. Malignant tumors within the past 5 years that have not been declared cured. 5. Vascular surgery or stent placement within the past year. 6. Severe or unstable symptomatic cardiovascular disease. 7. Evidence of severe or unstable physical conditions, such as acute or severe asthma, active peptic ulcers, severe liver disease, kidney disease requiring dialysis, or any other medical conditions that may interfere with completing the clinical trial. 8. Severe vision impairment, severe hearing loss, or communication difficulties that would prevent the participant from undergoing the intervention or efficacy assessments. 9. Abnormal findings in clinical pathology tests related to cognitive decline, as determined by the clinical investigator (e.g., significant thyroid dysfunction, vitamin B12 or folate deficiency, neurosyphilis, etc.). 10. The investigator's judgment that the participant is unlikely to cooperate fully with the study. 11. The investigator's judgment that the participant has difficulty safely participating in an exercise-based intervention program. 12. Participation in another interventional clinical trial.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Ajou University Hospital
Suwon, Gyeonggi-do, 16499, South Korea
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Bundang CHA General Hospital
Seongnam-si, Gyeonggi-do, South Korea
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Chonnam National University Hospital
Gwangju, South Korea
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Pusan National University Hospital
Busan, South Korea
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Other studies related to the condition(s) this trial covers.
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