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Targeted drug shows promise for rare cancers with cKIT mutation

NCT ID NCT06390826

First seen Nov 01, 2025 · Last updated Jun 16, 2026 · Updated 32 times

Summary

This study tests the drug sunitinib in people with advanced cancers that have a specific change in the cKIT gene. Sunitinib works by blocking signals that make cancer cells grow. The trial includes about 10 adults with lymphoma, solid tumors, or multiple myeloma that have not responded to other treatments. The main goal is to see if the drug can shrink or stop the cancer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • ECOG-ACRIN Cancer Research Group

    Philadelphia, Pennsylvania, 19103, United States

Conditions

The condition(s) this trial relates to.

cancer lymphoma plasma cell myeloma refractory hematologic cancer refractory malignant neoplasm refractory plasma cell neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.