Oxygen levels tracked in organ donation study
NCT ID NCT06780722
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study observes 50 adult organ donors to measure oxygen levels in the blood when the heart stops during a Maastricht III donation procedure. Researchers take blood samples at key moments to understand how low oxygen gets. The goal is to gather knowledge, not to test a treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could provide better data on oxygen levels during organ donation, potentially improving donation procedures.
- What could go wrong
- This is a small observational study (50 participants) that only measures existing events, not testing a new treatment. Results may not apply broadly.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2025
- Expected to finish
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Jun 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients who may be candidates for an organ donation procedure in the event of death in intensive care following the implementation of a procedure to discontinue active therapies.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
FOR THE DONORS : Inclusion Criteria : * Patient over 18 years of age * Organ donation procedure initiated in accordance with the legislation and procedures in force in France for the Maastricht III category * No opposition formulated by the relative to the patient's participation in the study Exclusion Criteria : * Patient registered on the national register of refusals or living refusal of donation * Pregnant or breast-feeding women * Patients under guardianship, curatorship or legal protection * Medical contraindication to organ donation according to the recommendations of the Agence de Biomédecine currently in force in France FOR THE RECEIVER Inclusion Criteria : * No opposition to the collection of data concerning him/her * Patient over 18 at pre-transplant consultation * Patient who has received an organ from a donor participating in the HEPHAISTOS protocol Exclusion Criteria : \- Patients under guardianship, curatorship or legal protection
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
12 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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CH ANNECY GENEVOIS - Réanimation médicale - Coordination Prélèvements multi-organes
RECRUITINGAnnecy, France
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CH AVIGNON - CH Henri Duffaut - Réanimation polyvalente
RECRUITINGAvignon, France
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CHBA Vannes-Auray - Réanimation Polyvalente
RECRUITINGVannes, France
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CHD Vendée - Les Oudairies - Médecine Intensive Réanimation
RECRUITINGLa Roche-sur-Yon, France
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CHRU ORLEANS -Médecine Intensive Réanimation - Coordination Prélèvements multi-organes
RECRUITINGOrléans, France
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CHRU TOURS - Hôpital Bretonneau - Médecine Intensive Réanimation
RECRUITINGTours, France
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CHU ANGERS - Réanimation médicale
RECRUITINGAngers, France
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CHU LILLE - Hôpital Roger Salengro - Médecine Intensive Réanimation
RECRUITINGLille, France
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CHU NANTES +- Médecine Intensive Réanimation
RECRUITINGNantes, France
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CHU POITIERS - Anesthésie Réanimation - Coordination Prélèvements multi-organes
NOT_YET_RECRUITINGPoitiers, France
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CHU RENNES - CHU Pontchaillou - Réanimation médicale
RECRUITINGRennes, France
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CHU de Nantes - Hôpital Laennec
RECRUITINGNantes, France
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Other studies related to the condition(s) this trial covers.
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