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Italian study tracks new antibody drugs for lymphoma patients

NCT ID NCT06008691

Knowledge-focused Sponsor: Fondazione Italiana Linfomi - ETS Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 1,500 people with B-cell non-Hodgkin lymphoma in Italy who are treated with newer monoclonal antibodies. Researchers will track how well the cancer responds, how long patients live without the disease getting worse, and any side effects. The goal is to see how these drugs perform in everyday medical practice, not in a controlled experiment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 1,500 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2023

Expected to finish

Oct 2038

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with diagnosis of B-cell NHL both first-line and relapsed or refractory aimed to be treated in indication with a "novel" MAB (alone or in combination) based on presence of an EMA clinical indication since 2020 and prescribed according to the indications for use authorized for marketing in Italy.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with diagnosis of B-cell NHL and need of treatment (as per guideline indications), both first-line and relapsed or refractory. * Patients aimed to be treated in indication with a "novel" MAB (alone or in combination) based on presence of an EMA clinical indication since 2020 and prescribed according to the indications for use authorized for marketing in Italy. * Signed written informed consent. Exclusion Criteria: * Being involved in a prospective interventional trial outside indication. * Patients treated outside approved indications: * 648-approved indication. * 5% AIFA support. * Compassionate use. * Age less than 18 years. * Inability to provide an informed consent.

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Conditions

The condition(s) this trial relates to.

B-cell non-Hodgkin lymphoma non-Hodgkin lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Non-Hodgkin lymphoma, B-cell

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    61 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • A.O. C. Panico - U.O.C Ematologia e Trapianto

    RECRUITING

    Tricase, Italy

  • A.O. Ospedali Riuniti Villa Sofia-Cervello - Divisione di Ematologia

    NOT_YET_RECRUITING

    Palermo, Italy

  • A.O. S. Croce e Carle - S.C. di Ematologia e Trapianto di Midollo Osseo

    RECRUITING

    Cuneo, Italy

  • A.O. S. Maria di Terni - S.C. Oncoematologia

    NOT_YET_RECRUITING

    Terni, Italy

  • A.O. SS. Antonio e Biagio e Cesare Arrigo - S.C. Ematologia

    RECRUITING

    Alessandria, Italy

  • A.O.R. "San Carlo" - U.O. Ematologia

    NOT_YET_RECRUITING

    Potenza, Italy

  • A.O.U. Città della Salute e della Scienza di Torino - Ematologia Universitaria

    RECRUITING

    Torino, Italy

  • A.O.U. Città della Salute e della Scienza di Torino - S.C. Ematologia

    RECRUITING

    Torino, Italy

  • AO Sant' Andrea - Ematologia

    RECRUITING

    Roma, Italy

  • AOU Federico II - Ematologia

    NOT_YET_RECRUITING

    Naples, Italy

  • AOU Integrata di Verona - U.O. Ematologia

    RECRUITING

    Verona, Italy

  • AOU Maggiore della Carità di Novara - SCDU Ematologia

    RECRUITING

    Novara, Italy

  • AOU Ospedali Riuniti - Clinica di Ematologia

    RECRUITING

    Ancona, Italy

  • AOU Senese - U.O.C. Ematologia

    RECRUITING

    Siena, Italy

  • AOU di Sassari - Ematologia

    NOT_YET_RECRUITING

    Sassari, Italy

  • ASST Cremona - Ematologia e CRTO

    RECRUITING

    Cremona, Italy

  • ASST Grande Ospedale Metropolitano Niguarda - SC Ematologia

    RECRUITING

    Milan, Italy

  • ASST Santi Paolo e Carlo - Onco - Ematologia

    RECRUITING

    Milan, Italy

  • ASST Spedali Civili di Brescia - Ematologia

    RECRUITING

    Brescia, Italy

  • Arnas Nuovo Ospedale Garibaldi Nesima - U.O.C. Ematologia

    RECRUITING

    Catania, Italy

  • Azienda Ospedaliera Papa Giovanni XXIII - Ematologia

    RECRUITING

    Bergamo, Italy

  • Azienda Ospedaliera S.Giuseppe Moscati - S.C. Ematologia e Trapianto emopoietico

    RECRUITING

    Avellino, Italy

  • Azienda Ospedaliera Universitaria Careggi - Unità funzionale di Ematologia

    RECRUITING

    Florence, Italy

  • Azienda Ospedaliera Universitaria Policlinico - S. Marco - UOC di Emtologia

    RECRUITING

    Catania, Italy

  • Azienda Sanitaria Universitaria Friuli Centrale (ASU FC) - SOC Clinica Ematologica

    RECRUITING

    Udine, Italy

  • Azienda Sanitaria Universitaria Giuliano Isontina (ASUGI) - SC Ematologia

    RECRUITING

    Trieste, Italy

  • Azienda Unità Sanitaria Locale-IRCCS - Arcispedale Santa Maria Nuova - Ematologia

    RECRUITING

    Reggio Emilia, Italy

  • Fondazione IRCCS Istituto Nazionale dei Tumori di Milano - Ematologia

    RECRUITING

    Milan, Italy

  • Fondazione IRCCS San Gerardo dei Tintori - Ematologia

    RECRUITING

    Monza, Italy

  • Fondazione del Piemonte per l'Oncologia - IRCCS - Ematologia

    RECRUITING

    Candiolo, Italy

  • I.R.C.C.S. Istituto Oncologico Veneto - Oncologia 1

    RECRUITING

    Padova, Italy

  • IRCCS Centro di Riferimento Oncologico di Aviano - Divisione di Oncologia e dei Tumori immuto-correlati

    RECRUITING

    Aviano, Italy

  • IRCCS Istituto Tumori Giovanni Paolo II - U.O.C Ematologia

    RECRUITING

    Bari, Italy

  • IRCCS Policlinico S. Matteo di Pavia - Div. di Ematologia

    NOT_YET_RECRUITING

    Pavia, Italy

  • IRCCS-Centro di Riferimento Oncologico - UO di ematologia e Trapianto Cellule Staminali

    RECRUITING

    Rionero in Vulture, Italy

  • Istituto Clinico Humanitas - U.O. Ematologia

    RECRUITING

    Rozzano, Italy

  • Istituto Oncologico del Mediterraneo SPA - Oncologico

    NOT_YET_RECRUITING

    Viagrande, Catania, Italy

  • Istituto Scientifico San Raffaele - Unità Linfomi - Dipartimento Oncoematologia

    RECRUITING

    Milan, Italy

  • Nuovo Ospedale Civile di Sassuolo - Day Hospital Oncologico

    RECRUITING

    Sassuolo, Italy

  • Nuovo Ospedale degli Infermi - SSD Ematologia

    RECRUITING

    Biella, Italy

  • Osp. civile di Carrara - Oncologia Medica

    RECRUITING

    Carrara, Italy

  • Ospedale "G. Mazzini" - UOS Ematologia

    NOT_YET_RECRUITING

    Teramo, Italy

  • Ospedale "Monsignor Raffaele Dimiccoli" - Ematologia

    NOT_YET_RECRUITING

    Barletta, Italy

  • Ospedale Apuane - Oncoematologia

    RECRUITING

    Massa, Italy

  • Ospedale Businco - SC Ematologia e CTMO

    NOT_YET_RECRUITING

    Cagliari, Italy

  • Ospedale Ca' Foncello - S.C di Ematologia

    RECRUITING

    Treviso, Italy

  • Ospedale Guglielmo da Saliceto - U.O. Ematologia

    RECRUITING

    Piacenza, Italy

  • Ospedale S.Stefano SOS Oncoematologia

    RECRUITING

    Prato, Italy

  • Ospedale SS. Cosma e Damiano - Ospedale San Jacopo - SOS Oncoematologia ed ematologia clinica

    RECRUITING

    Pescia, Pistoia, Italy

  • Ospedale Versilia USL NORDOVEST Toscana - UOS Ematologia

    RECRUITING

    Lido di Camaiore, Italy

  • Ospedale delle Croci - Ematologia

    RECRUITING

    Ravenna, Italy

  • Ospedale di Castelfranco Veneto - Ematologia

    RECRUITING

    Castelfranco Veneto, Italy

  • Ospedale di Civitanova Marche - UOSD EMATOLOGIA AREA VASTA 3 MACERATA

    RECRUITING

    Civitanova Marche, Italy

  • Ospedale di Livorno - Ematologia

    RECRUITING

    Livorno, Italy

  • P.O. Spirito Santo di Pescara - UOS Dipartimentale - Centro di diagnosi e Terapia dei linfomi

    RECRUITING

    Pescara, Italy

  • Policlinico S. Orsola-Malpighi - Istituto di Ematologia "Seragnoli"

    RECRUITING

    Bologna, Italy

  • Policlinico Umberto I - Università "La Sapienza" - Istituto Ematologia -Dipartimento di Medicina Traslazionale e di Precisione

    RECRUITING

    Roma, Italy

  • Policlinico Universitario Campus Bio-Medico - Ematologia - Trapianto cellule staminali - Medicina Trasfusionale e Terapia cellulare

    RECRUITING

    Roma, Italy

  • Presidio Ospedaliero F. Spaziani - UOC Ematologia

    RECRUITING

    Frosinone, Italy

  • Presidio ospedaliero "A. TORTORA" - U.O. Onco-ematologia

    NOT_YET_RECRUITING

    Pagani, Italy

  • ULSS 8 Berica - Ospedale S. Bortolo - Ematologia

    RECRUITING

    Vicenza, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.