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Promising heart drug study pulled before it even started

NCT ID NCT04843020

First seen Feb 21, 2026 · Last updated May 23, 2026 · Updated 14 times

Summary

This study aimed to see if a new drug, ION-682884, could slow or stop heart damage in people with TTR amyloidosis, a condition where abnormal protein builds up in the heart. Only patients who had already completed a 24-month study of a similar drug (inotersen) were eligible. The study was withdrawn before any participants enrolled, so no results are available.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

Conditions

Explore the condition pages connected to this study.