Strumming through treatment: can ukulele lessons shield teen brains from Radiation's toll?
NCT ID NCT07729384
First seen Jul 27, 2026 · Last updated Sep 11, 2026 · Updated 2 times
Summary
This pilot trial tests whether a program of virtual ukulele lessons, called STRUM, can help teenagers preserve cognitive function and emotional resilience while undergoing radiation therapy for cancer. The study enrolls adolescents aged 12 to 17 who are receiving initial radiation treatment with curative intent. Participants attend ten weekly 30-minute online ukulele sessions and practice independently, with researchers measuring feasibility, acceptability, and changes in brain resilience through cognitive testing.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- virtual music therapy ukulele lessons
- What this could lead to
- If it works, this could offer a simple, enjoyable way to help teens protect their memory and thinking skills during cancer treatment.
- What could go wrong
- This is a small pilot study focused on feasibility, not effectiveness. It may not show clear cognitive benefits, and results may not apply to all teens.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Oct 2026
An estimate. Start dates often move.
- Expected to finish
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Nov 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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12 to 17 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Aged 12-17 years at the time of enrollment * Receiving initial radiation therapy (RT) for cancer treatment with curative intent at the Mayo Clinic Arizona * Able to provide assent * Able to read and write in English * Have access to an electronic device with videoconferencing capability Exclusion Criteria: * Less than three-month prognosis * Past history of RT * Self-reported visual, hearing, or cognitive impairment impeding the ability to complete the STRUM intervention * Prior receipt of ukulele or guitar lessons * Actively receiving musical instrument lessons
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Mayo Clinic in Arizona
Scottsdale, Arizona, 85259, United States
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