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Zambia's new stroke unit could save lives

NCT ID NCT06457048

Disease control Sponsor: Johns Hopkins University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jul 29, 2026 · Updated 2 times

Summary

This study tested whether a specially designed stroke unit at the University Teaching Hospital in Lusaka, Zambia, improves care and survival for adults with stroke. The unit uses local protocols and trained staff to standardize treatment. Researchers compared outcomes for 300 patients treated in the unit to a historical group treated before the unit existed.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Stroke unit (specialized care protocols and trained staff)
What this could lead to
If successful, this could show that a low-cost, locally adapted stroke unit improves survival and quality of care in resource-limited settings.
What could go wrong
This is a single-site study comparing to historical data, so results may not apply elsewhere. The intervention is a care model, not a new drug, so benefits may be modest.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

300 people

The number who actually took part.

Started

Oct 2024

Finished

Aug 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Clinically suspected diagnosis of stroke by treating neurologist or imaging-confirmed diagnosis of stroke * Symptom onset (last known normal) within 7 days of presentation to the University Teaching Hospital in Lusaka, Zambia * Inpatient admission to the University Teaching Hospital in Lusaka, Zambia Exclusion Criteria: * Refusal to give informed consent

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Conditions

The condition(s) this trial relates to.

stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Stroke

Contacts and locations

Locations

  • University Teaching Hospital

    Lusaka, 00000, Zambia

More trials for these conditions

Other studies related to the condition(s) this trial covers.