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Clot removal success factors revealed in large stroke study

NCT ID NCT06016348

Knowledge-focused Sponsor: 115 People's Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looked at 400 stroke patients who had a clot-removal procedure (thrombectomy) within 24 hours of symptoms. Researchers wanted to find out which factors helped patients recover well, such as being able to walk independently. The goal is to better predict who benefits from this treatment, even when the stroke damage is large.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors identify which stroke patients are most likely to benefit from clot removal, even when the damage is large.
What could go wrong
This is an observational study, not a treatment trial. It only looks for patterns in past outcomes, so it cannot prove what works best for future patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

400 people

The number who actually took part.

Started

Jul 2023

Finished

Aug 2025

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

All adult patients underwent mechanical thrombectomy within 24 hours from symptom onset.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥ 18-year-old * Patients presenting with acute ischaemic stroke within 24 hours of stroke onset * Received mechanical thrombectomy within 24 hours of stroke onset * Imaging criteria include: * Large vessel occlusion on CT Angiography or MR Angiography (MRA) including tandem occlusion of the internal carotid artery and middle cerebral artery or internal carotid artery. * Core infarct criteria: 1. ASPECTS ≤5 on non-contrast CT or diffusion-weighted imaging (DWI). 2. ASPECTS score \>5 and core infarct volume of 50-150 ml on CT perfusion (CTP) or reduced cerebral blood flow (rCBF) \<30% on CTP or apparent diffusion coefficient (ADC) \<620 × 10-6 mm2/s on DWI. Exclusion Criteria: * Patients presenting with acute ischaemic stroke \>24 hours of stroke onset * Intracranial hemorrhage identified by CT or MRI * Pre-stroke modified Rankin Score (mRS) score of \>2 (indicating previous disability) * Any terminal illness such that the patient has a life expectancy of less than 1 year. * Patients with active cancer and undergoing treatment for cancer are excluded, * Pregnancy

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Conditions

The condition(s) this trial relates to.

ischemic stroke

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute ischemic stroke

Contacts and locations

Locations

  • 115 PEOPLE's HOSPITAL

    Ho Chi Minh City, 70000, Vietnam

  • Can Tho Central General Hospital

    Can Tho, Vietnam

  • Da Nang Stroke Center

    Da Nang, Vietnam

  • University Medical Center

    Ho Chi Minh City, 70000, Vietnam

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