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Zapping the brain to rewire stroke-damaged hands?

NCT ID NCT06809959

Knowledge-focused Sponsor: Universitätsklinikum Hamburg-Eppendorf Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a gentle, non-invasive brain stimulation technique called tACS could improve hand function in 20 stroke survivors. The stimulation targeted two key brain areas involved in movement planning. Researchers measured brain connectivity and hand movement patterns to see if the stimulation helped. The study was small and focused on measuring brain changes, not yet on proving a treatment works.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
transcranial alternating current stimulation (tACS) device
What this could lead to
If it works, this could point toward a non-invasive way to improve hand and arm recovery after stroke.
What could go wrong
This was a very small, early study (20 people) that looked at brain signals, not actual function. Results may not lead to a proven treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

20 people

The number who actually took part.

Started

Feb 2025

Finished

Apr 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * First-ever clinical stroke * Signed informed consent * First-ever clinical ischemic stroke at least 3 months ago * Stimulation areas (PMv and IPS) are unaffected * Residual deficits in the upper limb Exclusion Criteria: * Presence of additional neurological or psychiatric disorders * Use of psychotropic medication * Pregnancy or potential pregnancy in female participants * Pacemakers, other stimulators, or medication pumps * Claustrophobia * Non-MRI-compatible metallic implants or foreign objects in the body * Contraindications for transcranial alternating current stimulation (e.g., epilepsy, history of seizures, any type of pacemaker)

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Conditions

The condition(s) this trial relates to.

brain disorder cerebrovascular disorder stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Brain diseases Cerebrovascular disease Hand functions Stroke

Contacts and locations

Locations

  • Department of Neurology, University Medical Center Hamburg-Eppendorf

    Hamburg, 20246, Germany

More trials for these conditions

Other studies related to the condition(s) this trial covers.