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Brain zaps and recovery clues: study seeks to predict stroke rehab success

NCT ID NCT07520630

Knowledge-focused Sponsor: Moscow Scientific and Practical Center of Medical Rehabilitation, Restorative and Sports Medicine Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to find brain activity markers that can predict how well people recover after an ischemic stroke. Researchers will first study healthy volunteers to establish normal brain patterns, then test 120 stroke patients. Patients will receive either real or sham brain stimulation (called iTBS) along with standard rehab, and their brain activity and motor function will be measured. The goal is to build a model that forecasts rehabilitation outcomes, not to prove a new treatment works.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Intermittent Theta Burst Stimulation (iTBS) using a device
What this could lead to
If successful, this could lead to a personalized model that predicts how well a stroke patient will recover, helping doctors tailor rehabilitation more effectively.
What could go wrong
This is an early-stage study focused on finding markers, not testing a treatment. The brain stimulation may not improve outcomes, and results may not apply to all stroke patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 120 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

May 2026

An estimate. Start dates often move.

Expected to finish

Jun 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Experimental phase: will include healthy volunteers without contradictions to TMS Clinical phase: Inclusion Criteria: * First-ever ischemic stroke confirmed by CT/MRI * 5 days - 6 months post-stroke * Age 40-65 * MoCA ≥20 * HADS \<11 for anxiety and depression * MRC 2-4 in upper limb * Modified Ashworth Scale ≤3 * Signed informed consent Exclusion Criteria: * Implanted electronic devices * Epilepsy * Severe cardiac arrhythmias * Intracranial aneurysm * Decompensated somatic disease * Pregnancy/lactation

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Conditions

The condition(s) this trial relates to.

ischemic stroke

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Ischemic stroke Upper limb motor impairment

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Moscow Scientific and Practical Center of Medical Rehabilitation, Restorative and Sports Medicine

    Moscow, Russia

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