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Brain-Triggered zaps: new hope for stroke arm weakness?

NCT ID NCT07088107

Disease control Sponsor: The Hong Kong Polytechnic University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Sep 21, 2026 · Updated 2 times

Summary

This study tests a new device that uses brain signals to time magnetic pulses for stroke rehabilitation. The device reads blood flow changes in the brain and fires a magnetic pulse at the right moment to boost brain activity. Researchers will first test the system in healthy adults, then in 20 stroke survivors to see if it improves arm movement and brain excitability.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
fNIRS-triggered transcranial magnetic stimulation (TMS) device
What this could lead to
If successful, this could lead to a more personalized and effective brain stimulation therapy for stroke survivors, improving arm and hand movement.
What could go wrong
This is a very small, early-stage study (20 people) focused on testing the system's accuracy, not yet proving it works for recovery. The approach is complex and may not translate to real-world benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 20 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2025

Expected to finish

Dec 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Participants who meet the following criteria will be included: 1. Diagnosed with ischemic subcortical stroke, with stroke onset≥6 months. 2. Age between 18 and 80 years. 3. Residual upper limb functions between levels 2-7 in the FTHUE. 4. Capable of providing informed written consent. 5. Capable of reading and communicating with Chinese. Exclusion Criteria: Patients who meet any of the following criteria will be excluded: 1. any contraindications to TMS (screened by the safety checklist by Rossi). 2. signs of cognitive impairment, with a Montreal cognitive assessment score\<21/22 out of 30. 3. any moderate-to-severe chronic illness, such as uncontrolled hypertension, heart disease or renal failure. Healthy participants should be aged between 18 and 80, with no known history of neurological diseases. They should not have any moderate-to-severe chronic illness, such as uncontrolled hypertension, heart disease or renal failure.

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Conditions

The condition(s) this trial relates to.

ischemic stroke stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Stroke

Contacts and locations

Locations

  • Hong Kong Polytechnic University

    Hong Kong, 000000, Hong Kong

  • Hong Kong Polytechnic University - Brain Stimulation Laboratory

    Hong Kong, Hong Kong

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