Stroke's hidden toll on leg muscles revealed by ultrasound
NCT ID NCT07314918
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study used ultrasound to look at structural changes in the tibialis anterior muscle—important for lifting the foot—in 36 people who had a stroke. Researchers compared the affected leg to the unaffected leg and checked how muscle changes related to recovery. The goal was to better understand muscle remodeling after stroke, not to test a treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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36 people
The number who actually took part.
- Started
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May 2025
- Finished
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Dec 2025
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
This group consists of patients in the subacute and chronic phase post-stroke who are receiving inpatient treatment at the Istanbul Physical Therapy and Rehabilitation Training and Research Hospital.
- Ages
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40 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Male and female patients aged 40-80 years. * History of ischemic or hemorrhagic Cerebrovascular Accident (CVA). * Being in the subacute or chronic phase post-stroke. * Absence of communication deficits; ability to follow verbal commands. * Voluntary agreement to participate and provision of written informed consent. * Ability to ambulate without physical assistance from another person (use of assistive devices such as leg orthoses or tripods is permitted). Exclusion Criteria: * Presence of other comorbidities affecting gait (e.g., Parkinson's disease, hip surgery, etc.). * History of dyspnea (shortness of breath) during activities of daily living within the last 6 months. * Presence of bone or joint-related pain or pathology in the spine or hips. * Presence of psychiatric or cognitive disorders (e.g., learning disabilities, mental disorders, autism, etc.). * Decompensated cardiac, renal, or hepatic failure. * Presence of malignancy.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Istanbul, 34186, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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