Simple squeeze or a hand to hold may ease pain after knee replacement
NCT ID NCT06608264
First seen Jul 10, 2026 · Last updated Jul 10, 2026
Summary
This study tests whether squeezing a stress ball or holding a hand can reduce pain and improve mobility in people doing knee exercises after total knee replacement surgery. Participants are randomly assigned to use a stress ball, have their hand held by a loved one, or receive standard care during continuous passive motion exercises on the first and second days after surgery. Pain and mobility are measured before, during, and after the exercises to see if these simple, non-drug approaches help.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- stress ball and hand holding
- What this could lead to
- If effective, these simple, low-cost techniques could offer drug-free ways to manage pain and improve movement during recovery from knee replacement surgery.
- What could go wrong
- This is a small, early-stage trial with 78 patients, so results may not apply to everyone. The effects may be small or no different from standard care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
78 people
The number who actually took part.
- Started
-
Oct 2024
- Finished
-
Jul 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * After being informed about the study, written consent was obtained for voluntary participation * Able to speak Turkish and communicate verbally. * Those aged 18 and over * In the preoperative evaluation, the patient had an American Society of Anesthesiologists (ASA) score of I and II * A combination of spinal anesthesia and adductor block was applied during the surgery. * First-ever unilateral total knee arthroplasty performed * Total knee arthroplasty surgery is performed by the same physician and using the same surgical technique * Cooperative and oriented * Patients who underwent CPM placement after removal of the Hemovac drain on day 1 post-surgery were included in the study Exclusion Criteria: * Alzheimer, dementia-like conditions that prevent understanding * General anesthesia was administered during the surgery. * Patients who stay in the recovery unit for more than 1 hour (more than the routine period) after surgery or who receive treatment and care in the intensive care unit (patients whose vital signs are unstable, who develop lung problems, who are bleeding, who require blood transfusion, who have severe pain) * Patients with hemoglobin levels below 9 g/dL were excluded from the study. Exclusion criteria for monitoring/analysis * Total knee arthroplasty CPM application period after total knee arthroplasty ends earlier than 2 days * The study investigated complications that developed during the procedure after total knee arthroplasty (such as bleeding or dislocation) * Patients who decided to withdraw from the study during the implementation phase were planned to be excluded from monitoring/analysis.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Pain and mobility levels of patients undergoing total knee prosthesis during continuous passive motion exercise are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Aksaray Training and Research Hospital [Aksaray Eğitim ve Araştırma Hastanesi]
Aksaray, Aksaray/center, 68200, Turkey (Türkiye)