Simple squeeze or a hand to hold may ease pain after knee replacement

NCT ID NCT06608264

First seen Jul 10, 2026 · Last updated Jul 10, 2026

Summary

This study tests whether squeezing a stress ball or holding a hand can reduce pain and improve mobility in people doing knee exercises after total knee replacement surgery. Participants are randomly assigned to use a stress ball, have their hand held by a loved one, or receive standard care during continuous passive motion exercises on the first and second days after surgery. Pain and mobility are measured before, during, and after the exercises to see if these simple, non-drug approaches help.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
stress ball and hand holding
What this could lead to
If effective, these simple, low-cost techniques could offer drug-free ways to manage pain and improve movement during recovery from knee replacement surgery.
What could go wrong
This is a small, early-stage trial with 78 patients, so results may not apply to everyone. The effects may be small or no different from standard care.

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Conditions

The condition(s) this trial relates to.

Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Aksaray Training and Research Hospital [Aksaray Eğitim ve Araştırma Hastanesi]

    Aksaray, Aksaray/center, 68200, Turkey (Türkiye)