New stitch could slash hernia risk in cancer patients after major abdominal surgery
NCT ID NCT07218679
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two types of stitches used to close large abdominal incisions in cancer patients. One is a special barbed suture called Stratafix, and the other is a standard resorbable stitch. The goal is to see if Stratafix reduces the chance of developing an incisional hernia, a common complication after surgery. The trial involves 140 adults undergoing surgery for tumors in the abdomen or for cancer spread in the belly lining.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Stratafix suture (a barbed, coated stitch) and PDS Plus suture (a resorbable monofilament stitch)
- What this could lead to
- If it works, this could point toward a better way to close large abdominal incisions in cancer patients, reducing the risk of painful hernias after surgery.
- What could go wrong
- This is a relatively small, early-stage trial with 140 participants, so results may not apply to all patients. The study is not yet recruiting, and the intervention is a device, not a drug, so benefits may be modest.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 140 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2025
- Expected to finish
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Feb 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients over 18 years of age who will undergo midline laparotomy for oncologic resection of a retroperitoneal tumor or cytoreductive surgery for carcinomatosis of any origin. Exclusion Criteria: * Diagnosed incisional hernia. * When the planned midline laparotomy is expected to be less than 20 cm. * Patients with a BMI \> 45 kg/m². * Patients with abdominal aortic aneurysm. * Patients with coagulopathy: previously diagnosed with von Willebrand disease, hemophilia, or idiopathic thrombocytopenic purpura. * Patients with collagen disorders: previously diagnosed with Marfan syndrome, Ehlers-Danlos syndrome, homocystinuria, or scleroderma.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hospital Universitario Virgen del Rocio
Seville, 41013, Spain
More trials for these conditions
Other studies related to the condition(s) this trial covers.