Poop test predicts weight loss success after surgery?
NCT ID NCT07461610
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at 50 adults having either sleeve gastrectomy or gastric bypass to see if routine stool tests can reveal differences in gut function after surgery. Participants provide stool and blood samples before and 6 months after their operation. Researchers will check for signs of undigested food, gut inflammation, and changes in acidity to see if these relate to weight loss and diabetes improvement.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2026
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients with morbid obesity scheduled for primary bariatric surgery at Kasr Al-Ainy University Hospitals, Cairo, Egypt.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Male and female patients aged 18 to 60 years * Body Mass Index (BMI) ≥ 40 kg/m², OR BMI ≥ 35 kg/m² with at least one obesity-related comorbidity (type 2 diabetes, hypertension, dyslipidemia, osteoarthritis, obstructive sleep apnea) * Patients scheduled for primary laparoscopic bariatric surgery (either SG or Gastric Bypass \[MGB or RYGB\]) at Kasr Al-Ainy University Hospitals * Provision of written informed consent Exclusion Criteria: * Age \< 18 years or \> 60 years * Previous bariatric surgery or major gastrointestinal surgery (gastric, intestinal, or colorectal resection) * Chronic kidney disease (eGFR \< 60 mL/min/1.73m²) or previous renal transplant * Chronic liver disease (cirrhosis, chronic hepatitis) or liver failure * Chronic inflammatory bowel disease (Crohn's disease, ulcerative colitis), celiac disease, or chronic pancreatitis * Active malignancy or history of chemotherapy/radiotherapy in the past 5 years * Pregnancy or breastfeeding * Chronic alcohol abuse or substance abuse * Use of antibiotics, probiotics, or prebiotics within 4 weeks prior to stool sample collection (to avoid confounding effects on gut flora) * Acute gastrointestinal infection at the time of sample collection
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Faculty of Medicine Cairo University
RECRUITINGCairo, Al-Manial Cairo, 11956, Egypt
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