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Can a modified stomach bypass speed up recovery in advanced gastric cancer?

NCT ID NCT07749326

Disease control Sponsor: Gyeongsang National University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 06, 2026 · Last updated Aug 12, 2026 · Updated 4 times

Summary

This trial compares two surgical bypass procedures for people with advanced stomach cancer that blocks the passage of food. The standard approach connects the stomach directly to the small intestine, while the experimental approach adds a partial partition of the stomach to reduce the risk of delayed emptying. The study aims to see if the modified surgery helps patients eat sooner, recover faster, and begin chemotherapy earlier. Adults aged 20 to 85 with unresectable gastric cancer causing obstruction are eligible to participate.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Two surgical procedures: conventional laparoscopic gastrojejunostomy and stomach-partitioning laparoscopic gastrojejunostomy
What this could lead to
If successful, this could establish a new standard palliative surgery that helps people with advanced stomach cancer eat sooner, leave the hospital faster, and start chemotherapy earlier.
What could go wrong
This is a randomized trial, but results may not apply to all patients. The stomach-partitioning technique carries surgical risks, and the expected benefit in reducing delayed gastric emptying may not be confirmed.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 144 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2026

Expected to finish

Jul 2030

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 85 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Histologically confirmed gastric adenocarcinoma with Gastric Outlet Obstruction (GOO) that is unresectable for cure (e.g., surrounding tissue invasion, localized peritoneal metastasis, distant metastasis) * Tumor location confined to the lower one-third (Low body 1/3) of the stomach ③ Age between 20 and 85 years * ECOG Performance Status ≤ 2 ⑤ ASA score Class I to III ⑥ Endoscopic or radiologic evidence of obstructive GOO Exclusion Criteria: * Patients with bowel obstruction due to extensive peritoneal metastasis (P3) * Tumor extension beyond the lower one-third into the middle one-third of the stomach, making partitioning difficult ③ Patients requiring emergency surgery for perforation or hemorrhage ④ Severe malnutrition (serum albumin \< 2.5} g/L) ⑤ Patients currently undergoing pre-operative chemotherapy

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Conditions

The condition(s) this trial relates to.

gastric adenocarcinoma gastric neoplasm pyloric stenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Gastric outlet obstruction Gastric outlet obstruction due to gastric adenocarcinoma Palliative surgery Stomach neoplasms

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Gyeongsang National University Changwon hospital

    RECRUITING

    Changwon, Gyeongsangnam-do, 51472, South Korea

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