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Honey as a mood booster? small study tests stingless bee honey for depression

NCT ID NCT06723249

Symptom relief Sponsor: Hospital Universiti Sains Malaysia Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether taking stingless bee honey daily for two months could improve depression symptoms, memory, and stress markers in adults with major depressive disorder. 45 participants either took the honey or nothing (no placebo). Researchers measured mood, blood markers, and verbal memory. The goal was to see if honey could be a helpful add-on to standard care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
stingless bee honey
What this could lead to
If it works, this could point toward a natural supplement to help ease depression symptoms and improve memory.
What could go wrong
This is a small, completed trial with no placebo, so results may be unreliable. The honey is a supplement, not a replacement for standard depression treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

45 people

The number who actually took part.

Started

Dec 2024

Finished

Aug 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults with ages 18 to 65 * with Major Depressive Disorder with scores of Beck Depression Inventory Malay version equal or more than 11 Exclusion Criteria: * Women in pregnancy or breast-feeding. * Patients who with honey allergy or stingless bee honey allergy. * Currently taking honey not limited to stingless bee honey or taken honey not limited to stingless bee honey in the past one month. * comorbidity either with generalized anxiety disorder, * panic disorder, * social anxiety disorder, * bipolar disorder, * substance-use disorder, * suicidal ideation or attempt, * dementia, * Alzheimer disease, * diabetic, * hypertension, * chronic kidney disease

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Conditions

The condition(s) this trial relates to.

major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Major depressive disorder (MDD)

Contacts and locations

Locations

  • Hospital Universiti Sains Malaysia

    Kubang Kerian, Kelantan, 16150, Malaysia

More trials for these conditions

Other studies related to the condition(s) this trial covers.