Massive trial aims to crack the code of Post–Cardiac arrest care
NCT ID NCT05564754
First seen Jun 02, 2026 · Last updated Jun 22, 2026 · Updated 5 times
Summary
This study looks at 3,500 people who were revived after a cardiac arrest but remain unconscious. It tests three key ICU decisions: how deeply to sedate, whether to actively control fever, and what blood pressure target to aim for. The goal is to find which combination saves more lives and leads to better brain recovery.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Austin Hospital
Melbourne, Victoria, Australia
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Bern University Hospital
Bern, Switzerland
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Bristol Royal Infirmary
Bristol, United Kingdom
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Cardiff University Hospital
Cardiff, United Kingdom
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Centre Hospitalier de Luxembourg
Luxembourg, Luxembourg
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Charite University Hospital
Berlin, Germany
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Christchurch Hospital
Christchurch, New Zealand
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DCCM ICU
Auckland, New Zealand
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Essex Cardiothoracic Centre
Basildon, United Kingdom
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Ghent University Hospital
Ghent, 9000, Belgium
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HUB Hôpital Erasme
Brussels, 1077, Belgium
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Hallands hospital
Halmstad, Halland County, Sweden
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Helsingborg Hospital
Helsingborg, Skåne County, Sweden
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Helsinki Helsingforgs University Central Hospital
Helsinki, Finland
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Jorvi Hospital
Espoo, Finland
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Jyväskylä Hospital
Jyväskylä, Finland
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Kalnes Hospital
Kalnes, Norway
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Karlstad hospital
Karlstad, Sweden
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Karolinska University Hospital
Stockholm, Sweden
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King Abdulaziz Medical City
Riyadh, Saudi Arabia
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Kings College Hospital
London, United Kingdom
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Kuopio University Hospital
Kuopio, Finland
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Leeds General Infirmary
Leeds, United Kingdom
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Liverpool Hospital
Liverpool, New South Wales, Australia
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Lübeck University Hospital
Lübeck, Germany
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Meilahti Hospital
Helsinki, 00290, Finland
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Middlemore ICU
Auckland, New Zealand
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Nepean Hospital
Kingswood, New South Wales, Australia
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North Estonia Medical Centre, Tallinn
Tallinn, 13409, Estonia
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North Shore ICU NZ
Auckland, New Zealand
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Oslo University Hospital
Oslo, Norway
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Oulu University Hospital
Oulu, Finland
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Princess Alexandra Hospital
Brisbane, Queensland, Australia
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Royal North Shore Hospital
Sydney, New South Wales, Australia
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Sahlgrenska University Hospital
Gothenburg, Sweden
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San Martino Hospital Genova
Genova, Italy
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Skaraborg Hospital Skovde
Skövde, Sweden
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Skåne University Hospital
Lund, Skåne County, Sweden
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Skåne University Hospital Malmö
Malmö, Skåne County, Sweden
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Soerlandet Hospital Arendal
Arendal, Norway
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St Bartholomew's Hospital
London, United Kingdom
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St Gallen Hospital
Sankt Gallen, Switzerland
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St George Hospital
Sydney, New South Wales, Australia
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St Georges University Hospital
London, United Kingdom
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St Vincents University Hospital
Dublin, Ireland
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Stavanger University Hospital
Stavanger, Norway
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Tampere University Hospital
Tampere, Finland
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Tan Tock Seng Hospital
Singapore, Singapore
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The Prince Charles Hospital
Brisbane, Queensland, Australia
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The Sutherland Hospital
Sydney, New South Wales, Australia
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Tubingen University Hospital
Tübingen, Germany
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University Hospital Zürich
Zurich, Switzerland
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University Hospital of Umeå
Umeå, Sweden
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Wellington Hospital
Wellington, New Zealand
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Whangarei ICU
Northland, New Zealand
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Ziekenhuis Oost-Limburg Hospital
Lanaken, 3620, Belgium
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Intensive care strategies (sedation, temperature control, blood pressure management)
What this could lead to
If successful, this could identify the best combination of ICU treatments to reduce deaths and improve brain function after cardiac arrest.
What could go wrong
This is a large trial, but it tests existing treatments in new ways—results may show no clear winner or only small differences. Individual patient responses can vary widely.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.