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Blood test may match relapsed lung cancer patients to better treatment

NCT ID NCT06681220

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 27 times

Summary

This study tests whether a blood biomarker can identify people with relapsed small cell lung cancer who will benefit from a new oral drug combination (stenoparib plus temozolomide) compared to standard chemotherapy (lurbinectedin). About 166 adults who have already had one round of chemo will participate. The goal is to see if the biomarker-guided approach improves how long the cancer stays under control.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA

    RECRUITING

    Philadelphia, Pennsylvania, 19104-4551, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Jesse Brown VA Medical Center, Chicago, IL

    NOT_YET_RECRUITING

    Chicago, Illinois, 60612, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Michael E. DeBakey VA Medical Center, Houston, TX

    RECRUITING

    Houston, Texas, 77030-4211, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Minneapolis VA Health Care System, Minneapolis, MN

    NOT_YET_RECRUITING

    Minneapolis, Minnesota, 55417-2309, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Omaha VA Nebraska-Western Iowa Health Care System, Omaha, NE

    NOT_YET_RECRUITING

    Omaha, Nebraska, 68105-1850, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Richard L. Roudebush VA Medical Center, Indianapolis, IN

    RECRUITING

    Indianapolis, Indiana, 46202-2884, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Robley Rex VA Medical Center, Louisville, KY

    NOT_YET_RECRUITING

    Louisville, Kentucky, 40206-1433, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Salisbury W.G. (Bill) Hefner VA Medical Center, Salisbury, NC

    RECRUITING

    Salisbury, North Carolina, 28144, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • VA Ann Arbor Healthcare System, Ann Arbor, MI

    NOT_YET_RECRUITING

    Ann Arbor, Michigan, 48105-2303, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • VA Palo Alto Health Care System, Palo Alto, CA

    RECRUITING

    Palo Alto, California, 94304-1207, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA

    RECRUITING

    Pittsburgh, Pennsylvania, 15240, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.