Desperate for relief: one patient gets experimental stem cell infusions for chronic pain
NCT ID NCT04711811
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This trial gave multiple infusions of a patient's own stem cells to treat chronic muscle and joint pain that had lasted at least a year. The patient received six infusions over about 32 weeks, with safety checks and pain scores tracked throughout. The goal was to see if this approach could safely ease pain and improve daily life.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- patient's own stem cells (Hope Biosciences adipose derived autologous mesenchymal stem cells)
- What this could lead to
- If it works, this could point toward a way to reduce chronic pain without long-term medication.
- What could go wrong
- This was a very small, early access program for just one patient, so results may not apply to others. The treatment is still experimental and unproven.
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Study facts
What this study's own registry entry says, in plain language.
- Lead sponsor
-
A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
IND # 27057 Inclusion Criteria: 1. Subject is \> 18 years of age at the time of signing the informed consent form. 2. Subject has the diagnosis of chronic musculoskeletal pain for a least 1 year or VAS score \> 7 a screening visit. 3. Subject has provided informed consent before initiation of any study procedure. 4. Subject and sexual partner if woman of childbearing potential must use a least 1 highly effective form of birth control\* throughout the study and for 6 months after the last dose of the investigational product. Exclusion Criteria: 1. Subject has any active infection for which antibiotics were indicated within 4 weeks before screening. 2. Subject has known alcoholic addiction or dependency, uses alcohol daily, or has current substance use or abuse. 3. Subject has any active malignancy, including evidence of cutaneous basal, squamous cell carcinoma, or melanoma. 4. Subject has 1 or more significant concurrent medical conditions per investigator judgment, including the following: * poorly controlled diabetes. * chronic kidney disease * heart failure * myocardial infarction or unstable angina within 6 months prior to screening. * uncontrolled hypertension 5. Subject has received any stem cell treatment within 12 months before first dose of investigational product. 6. Subject has laboratory abnormalities during screening, including the following: * White blood cell count \< 3000/mm3 * Platelet count \< 125,000mm3 * Absolute neutrophil count \< 1500/mm3 * Subject has any other laboratory abnormality, which, in the opinion of the investigator poses a safety risk or will prevent the subject for completing the study. 7. Subject is currently receiving treatment in another investigational drug study. 8. Subject is unlikely to complete the study or adhere to the study procedures.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hope Biosciences Stem Cell Research Foundation
Sugar Land, Texas, 77478, United States
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