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New transplant approach aims to fix immune system in rare diseases

NCT ID NCT04232085

First seen Jan 04, 2026 · Last updated May 22, 2026 · Updated 21 times

Summary

This study tests a stem cell transplant using milder chemotherapy for people with certain immune deficiencies or bone marrow failure. The goal is to see if donor cells can take over the bone marrow and restore a working immune system. About 27 participants will be enrolled, and the main measure is whether donor cells make up at least 95% of blood cells by day 60.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Johns Hopkins University

    RECRUITING

    Baltimore, Maryland, 21287, United States

    Contact

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.