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Stem cells armed to attack recurrent brain cancer in early trial

NCT ID NCT02192359

First seen Nov 15, 2025 · Last updated May 18, 2026 · Updated 27 times

Summary

This early-phase study tests a new approach for people with high-grade gliomas (aggressive brain tumors) that have come back after previous treatment. Researchers place genetically modified neural stem cells directly into the brain tumor to make it more sensitive to the chemotherapy drug irinotecan. The main goal is to find the safest dose and check for side effects in 18 participants.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • City of Hope Medical Center

    Duarte, California, 91010, United States

Conditions

Explore the condition pages connected to this study.