New study aims to cut seizure treatment time in kids
NCT ID NCT06194747
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a set of hospital improvements can help doctors treat children with prolonged seizures (status epilepticus) faster. About 450 children will take part. The goal is to give seizure-stopping medicine within minutes of diagnosis, which may lower the risk of brain damage or death.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 450 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2024
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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30 days to 18 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * SE episode occurs in a male or female child aged between \> 30 days to \< 19 years * Seizures meeting AT LEAST ONE of the following criteria: 1. continuous clinically apparent seizure lasting greater than 5 minutes 2. continuous clinically apparent seizure of any duration receiving BZD 3. repeated seizures without return to neurological baseline within 5 minutes Exclusion Criteria: * SE episode occurs in a child with infantile spasms * SE episode occurs in a child with electrographic-only seizures without clinical signs other than encephalopathy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Nationwide Children's Hospital
RECRUITINGColumbus, Ohio, 43205, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Brain wave battle: deeper suppression may halt post-arrest seizures
- Seizure drug may shield the brain after cardiac arrest — a trial puts it to the test
- Brain rescue: dual drug attack on Post-Arrest seizures shows promise
- Can a half-day training sharpen ICU nurses' ability to detect hidden seizures?
- Life after a seizure emergency: study tracks hidden toll on mind and body
- Massive brain injury study aims to unlock secrets of recovery