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70,000 patients studied: do statins help or hinder surgery recovery?

NCT ID NCT07575737

Knowledge-focused Sponsor: Karolinska Institutet Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at 70,000 adults who had major non-cardiac surgery to see if taking statins before surgery affected their chances of survival and how quickly they recovered at home. Researchers tracked deaths within 30 days and one year, as well as days spent at home after surgery. The goal was to understand whether statins' anti-inflammatory effects could reduce complications from the stress of surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
statins
What this could lead to
If the results show a clear benefit, it could guide doctors on using statins to improve outcomes after major surgery.
What could go wrong
This is an observational study, not a controlled trial, so it can only show links, not cause and effect. Other factors like overall health may influence the results.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

70,000 people

The number who actually took part.

Started

May 2024

Finished

Feb 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients (equal to or over 18 years) undergoing elective non-cardiac surgery

Ages

18 years and older

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged ≥ 18 years at the time of surgery * Elective (non-emergency) surgical procedure * Non-cardiac surgery (all surgical specialties except cardiac surgery) Exclusion Criteria: * Obstetric surgery * Transplant surgery * Planned day-case surgery (procedures with intended same-day discharge) * Anesthetic monitoring episodes not involving a surgical procedure (e.g., anesthetic support for central venous catheter insertion) * Urological brachytherapy * Stereotactic radiosurgery (Gamma Knife or equivalent) * Repeat or subsequent surgical procedures during the study period - only the index (chronologically first eligible) procedure per patient is included in the analysis

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Perioperative care

Contacts and locations

Locations

  • Karolinska University Hospital Huddinge

    Stockholm, Sweden

  • Karolinska University Hospital Solna

    Stockholm, Sweden

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