Scientists track how aging changes arthritis symptoms and thinking skills
NCT ID NCT05463666
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how getting older affects disease activity, memory, and physical function in people with rheumatoid arthritis (RA) compared to those without RA. Researchers will follow 840 adults aged 55-85, half with RA and half without, using questionnaires and physical tests. The goal is to create age-specific reference charts to help doctors better interpret test results in older adults.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 840 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2022
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
RA patients for the STAR project will be recruited from the outpatient clinics of the MUMC and the Zuyderland Medical Center in Heerlen / Sittard by the rheumatologist. The control population will be recruited through friends and/or family members of patients and controls, snowball sampling; a qualified participant can share an invitation with other subjects similar to them, and recruitment via patient partners of the MUMC. Moreover, patients and controls will be recruited by giving a presentation about the study during a gathering of patients and their family at the Reumacafé, dissemination of flyers during regular information evening of the department of rheumatology at the MUMC and Zuyderland, and recruit via local social (sports) clubs.
- Ages
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55 to 85 years
- Sex
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Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria (RA population): * Age between 55-85 years at baseline. * Diagnosis of RA by treating rheumatologist. Inclusion Criteria (control population): * Age between 55-85 years at baseline. * No diagnosis of RA, or other inflammatory RMD (osteoarthritis allowed). Exclusion Criteria: * Subject is the spouse/partner of the included RA patient. * Have severe comorbidity and the treating rheumatologist and/or research team decides they should not be included in the study because of health reasons. * A diagnosis of dementia or mental incompetency is always reason for exclusion. * Persons of whom the research team estimates that his/her life expectancy is less than 2 years. * Do not understand the Dutch language and/or are notable to understand the study information.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Maastricht UMC+
Maastricht, Limburg, 6229HX, Netherlands
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Other studies related to the condition(s) this trial covers.
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