New hope for advanced prostate cancer: STAMPEDE2 trial tests targeted radiation and radioactive drug

NCT ID NCT06320067

Recruiting now Disease control Sponsor: University College, London Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 20, 2026 · Updated 28 times

Summary

This large phase 3 trial tests two new treatments for prostate cancer that has spread. One uses targeted radiation (SABR) to kill cancer spots, the other uses a radioactive drug (PSMA-Lutetium) that seeks out prostate cancer cells. About 3,360 people will take part, and all continue standard hormone therapy. The goal is to see if these added treatments slow cancer growth and help people live longer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

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Locations

Addenbrookes
RECRUITING

Cambridge, United Kingdom
Barking, Havering and Redbridge University Hospitals NHS Trust
RECRUITING

Romford, United Kingdom
Barts Health NHS Trust
RECRUITING

London, United Kingdom
Churchill Hospital
RECRUITING

Oxford, United Kingdom
Derriford Hospital
RECRUITING

Plymouth, United Kingdom
Kings Mill Hospital
RECRUITING

Sutton in Ashfield, United Kingdom
Mount Vernon Hospital
RECRUITING

Barnsley, United Kingdom
North Middlesex Hospital
RECRUITING

London, United Kingdom
North Tees Health NHS Trust
RECRUITING

Stockton-on-Tees, United Kingdom
Queen Alexandra Hospital
RECRUITING

Portsmouth, United Kingdom
Royal Devon & Exeter Hospital
RECRUITING

Exeter, United Kingdom
Royal Devon University Hospital Trust
RECRUITING

Exeter, EX2 5DW, United Kingdom
Royal Free Hospital
RECRUITING

London, United Kingdom
The James Cook University Hospital
RECRUITING

Middlesbrough, United Kingdom
The Princess Alexandra Hospital
RECRUITING

Harlow, United Kingdom
The Royal Marsden Hospital
RECRUITING

London, SW3 6JJ, United Kingdom
The Royal Marsden Hospital
RECRUITING

Sutton, SM2 5PT, United Kingdom
University College London Hospitals NHS Foundation Trust
RECRUITING

London, NW3 2PG, United Kingdom

Conditions

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PROSTATE CANCER METASTATIC