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Light-Based scanner spots early tooth erosion before It's visible

NCT ID NCT07690644

Diagnosis Sponsor: University of Malaya Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time

Summary

This study tests whether a non-invasive imaging tool called swept-source optical coherence tomography (SS-OCT) can detect early signs of tooth erosion caused by acidic drinks. Twenty-two healthy adults swished orange juice repeatedly over three days, and their teeth were scanned with SS-OCT to measure changes in enamel. The study also looked at whether chewing sugar-free gum after the acid exposure could help protect the teeth. The goal is to see if this technology could be used in dental clinics to catch erosion early and guide prevention.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Swept-Source Optical Coherence Tomography (SS-OCT)
What this could lead to
If successful, this imaging method could help dentists catch tooth erosion earlier and test simple preventive measures like chewing gum.
What could go wrong
This is a small, early-stage study in healthy adults, so results may not apply to everyone. The imaging technique may not be sensitive enough for routine dental use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

22 people

The number who actually took part.

Started

Jun 2016

Finished

Jun 2016

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

22 to 33 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Healthy adults aged 23-33 years. Presence of intact maxillary right central incisor (tooth 11) suitable for repeated SS-OCT imaging. Good general and oral health. Normal unstimulated salivary flow rate (≥0.2 mL/min). Willingness to comply with all study procedures, including repeated erosive challenges and SS-OCT examinations. Provision of written informed consent prior to participation.- Exclusion Criteria: Presence of active dental caries, restorations, enamel defects, cracks, or erosive lesions on the study tooth. Ongoing orthodontic treatment affecting the study tooth. History of systemic diseases or medications known to affect salivary flow or enamel mineralization. Unstimulated salivary flow rate \<0.2 mL/min. Pregnancy or breastfeeding. Known allergy or intolerance to orange juice or sugar-free chewing gum. Current smokers or tobacco users. Inability or unwillingness to comply with study procedures or attend all scheduled visits.

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Conditions

The condition(s) this trial relates to.

tooth erosion, non-bacterial

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dental erosion Erosive tooth wear

More trials for these conditions

Other studies related to the condition(s) this trial covers.