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New study aims to read skin cancer depth from photos

NCT ID NCT07384949

Knowledge-focused Sponsor: Istanbul Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks back at 238 patients with a common skin cancer called squamous cell carcinoma. Researchers will compare special skin photos (dermoscopic images) with lab results from removed tumors. The goal is to see if certain features in the photos can tell how deep the cancer has grown, which could help guide treatment decisions in the future.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors better predict tumor depth from skin images, potentially reducing the need for some biopsies.
What could go wrong
This is a retrospective, observational study, so it cannot prove cause and effect. Results may not apply to all patients or change current practice directly.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 238 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Feb 2026

An estimate. Start dates often move.

Expected to finish

Jun 2026

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consists of adult patients aged 18 to 100 years who were diagnosed with cutaneous squamous cell carcinoma and treated with total surgical excision between 2016 and 2025. Only cases with complete clinical, dermoscopic, and histopathological records, including documented tumor differentiation and invasion depth, were included. No additional diagnostic or therapeutic procedures were performed as part of the study.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria:Age between 18 and 100 years at the time of diagnosis Histopathologically confirmed cutaneous squamous cell carcinoma Lesions that underwent total surgical excision Histopathology reports including both tumor differentiation grade and invasion depth Availability of dermoscopic images obtained prior to excision Dermoscopic images of sufficient quality for evaluation and image analysis - Exclusion Criteria: Lesions that received any prior treatment, including radiotherapy, chemotherapy, cryotherapy, or other destructive or topical treatments before excision Incomplete clinical, dermoscopic, or histopathological data Poor-quality dermoscopic images not suitable for reliable evaluation or segmentation \-

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Conditions

The condition(s) this trial relates to.

skin squamous cell carcinoma squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cutaneous squamous cell cancer

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University of Health Sciences, Istanbul Training and Research Hospital, Department of Dermatology

    Istanbul, FATİH, 34098, Turkey (Türkiye)

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