New breathing device may help CF patients produce mucus for testing
NCT ID NCT06311292
First seen Apr 30, 2026 · Last updated Jun 23, 2026 · Updated 10 times
Summary
This small pilot study tested whether a breathing device called the Volara System could help adults with cystic fibrosis produce sputum (mucus from the lungs) for lab testing. The study included 20 people who had not been able to produce a sputum sample in the past year. Participants used the device during a clinic visit to try to loosen and collect mucus. The goal was to see if this method could provide enough sputum for a successful culture result.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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UPMC Presbyterian Hospital
Pittsburgh, Pennsylvania, 15213, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Volara System (a breathing device that delivers gentle air pulses to loosen mucus)
What this could lead to
If successful, this method could give doctors a better way to collect sputum for infection testing in people with cystic fibrosis who struggle to cough up mucus.
What could go wrong
This is a very small pilot study (20 people) with no comparison group, so results may not apply to everyone. The device may not work for all patients.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.