Could a common pill protect new Moms' hearts after preeclampsia?
NCT ID NCT07041281
First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 31 times
Summary
This study tests whether spironolactone, a blood pressure drug, can help women who had high blood pressure during pregnancy (preeclampsia or gestational hypertension) and are overweight. About 204 women will take either spironolactone or a placebo daily for 12 weeks after giving birth. Researchers will check their blood pressure and heart structure nine months later to see if the drug reduces long-term heart risks.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Brigham and Women's Hospital
RECRUITINGBoston, Massachusetts, 02115, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Pittsburgh Magee-Womens Hospital
NOT_YET_RECRUITINGPittsburgh, Pennsylvania, 15213, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
spironolactone
What this could lead to
If it works, this could point toward a simple daily pill to help women with past hypertensive pregnancy avoid long-term high blood pressure and heart problems.
What could go wrong
This is a mid-stage trial with 204 participants, so results are not final. Spironolactone can cause side effects like high potassium or kidney issues, and it may not improve heart health as hoped.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.