10,500 volunteers needed to unlock secrets of back pain
NCT ID NCT05776771
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This observational study aims to understand differences between people with and without low back or neck pain by comparing their health history and movement. Over 10,000 participants will wear motion sensors and complete questionnaires in a single session, with follow-ups over 5 years. The goal is to develop better ways to predict injury, identify patient types, and evaluate treatments for spine pain.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 10,500 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2020
- Expected to finish
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Dec 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
There are 3 different study populations: Controls/Insincere, Low Back Pain, and Neck Pain
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Controls/Insincere Inclusion Criteria * Age 18 and older * Able to stand for 20 minutes * Able to speak, read, and understand English Exclusion criteria: * Known pregnancy * Currently seeing or planning to see a medical provider for low back or neck pain * History of chronic low back or neck pain lasting longer than 3 months * Blind or severe uncorrected vision problems that prevent participant from reading a tablet or laptop screen * Deaf or hearing problems that prevent the participant from hearing verbal instructions * Actively being treated by a medical provider for concussion * Known severe spinal deformity requiring medical treatment (e.g. scoliosis) * Has been diagnosed by a medical provider with severe vertigo, fainting, narcolepsy, or balance disorders with high risk for falling * Any known fractures within the last 3 months that will interfere with the motion assessment * History of spine fracture * Current condition requiring immobilization or bracing of the spine * History of spine surgery (e.g. fusion, micro-discectomy, or artificial disc replacement) * History of brain or spine cancer * Currently or within the last 90 days, been treated for cancer with chemotherapy or radiation therapy * Known severe osteoporosis requiring medical treatment and physician-recommended physical restrictions * Current open wounds or medical device entry points where the harnesses will be placed on the neck, back, or hips * Current osteomyelitis or spine infection * Any other reason that a treating physician, researcher, or participant determines it is unsafe for a patient to perform test Low Back Pain Patients Inclusion Criteria * Age 18 and older * Currently seeking medical consult with primary complaint of low back pain * Able to speak, read, and understand English * Able to stand for 10 minutes Exclusion criteria: * Known pregnancy * Blind or severe uncorrected vision problems that prevent participant from reading a tablet or laptop screen * Deaf or hearing problems that prevent the participant from hearing verbal instructions * Current low back pain is the result of a traumatic injury (wreck, fall, etc.) that occurred within the last 3 months OR is positive for spine instability with imaging * Has spinal fusion across 4 or more lumbar disc levels. * Actively being treated by a medical provider for concussion * Known severe spinal deformity requiring medical treatment (e.g. scoliosis) * Has been diagnosed by a medical provider with severe vertigo, fainting, narcolepsy, or balance disorders with high risk for falling * Any known fractures within the last 3 months that will interfere with the motion assessment * Any known spine fractures within the last 6 months * Known unstable spondylolisthesis (i.e. standing 3mm of movement on flexion/extension film) * Current condition requiring immobilization of the spine * History of brain or spine cancer * Currently or within the last 90 days, been treated for any cancer with chemotherapy or radiation therapy * Known severe osteoporosis requiring medical treatment and physician-recommended physical restrictions * Current open wounds or medical device entry points where the harnesses will be placed on the back or hips * Current osteomyelitis or spine infection * Any other reason that a treating physician, researcher, or participant determines it is unsafe for a patient to perform test Neck Pain Patients Inclusion Criteria * Age 18 and older * Currently seeking medical consult with primary complaint of neck pain * Able to speak, read, and understand English * Able to stand for 10 minutes Exclusion criteria: * Known pregnancy * Blind or severe uncorrected vision problems that prevent participant from reading a tablet or laptop screen * Deaf or hearing problems that prevent the participant from hearing verbal instructions * Current neck pain is the result of a traumatic injury (wreck, fall, etc.) that occurred within the last 3 months OR is positive for spine instability with imaging * Has spinal fusion across 4 or more cervical disc levels or an occipital-cervical fusion. * Actively being treated by a medical provider for concussion * Known severe spinal deformity requiring medical treatment (e.g. scoliosis) * Has been diagnosed by a medical provider with severe vertigo, fainting, narcolepsy, or balance disorders with high risk for falling * Any known fractures within the last 3 months that will interfere with the motion assessment * Any known spine fractures within the last 6 months * Known unstable spondylolisthesis (i.e. standing 3mm of movement on flexion/extension film) * Current condition requiring immobilization of the spine * History of brain or spine cancer * Currently or within the last 90 days, been treated for any cancer with chemotherapy or radiation therapy * Known severe osteoporosis requiring medical treatment and physician-recommended physical restrictions * Current open wounds or medical device entry points where the harnesses will be placed on the neck or back * Current osteomyelitis or spine infection * Any other reason that a treating physician, researcher, or participant determines it is unsafe for a patient to perform test
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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The Ohio State University Wexner Medical Center
RECRUITINGColumbus, Ohio, 43210, United States
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Other studies related to the condition(s) this trial covers.
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