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New pill targets hormone imbalance from adrenal growths

NCT ID NCT05436639

First seen Feb 15, 2026 · Last updated May 22, 2026 · Updated 13 times

Summary

This study tested a daily pill called SPI-62 in 30 adults with high cortisol levels caused by a non-cancerous adrenal tumor. The goal was to see if the drug could improve blood sugar control and reduce cortisol-related health problems. Participants took 2 mg of SPI-62 each day for up to 12 weeks, and researchers measured changes in blood sugar and safety.

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Contacts and locations

Locations

  • C.M.D.T.A. Neomed

    Brasov, 500283, Romania

  • Institutul National de Endocrinologie

    Bucharest, 11863, Romania

  • King's College Hospital

    London, SW9 8RR, United Kingdom

  • Mayo Clinic Cancer Center (MCCC) - Rochester

    Rochester, Minnesota, 55905, United States

  • Ohio State McCampbell Outpatient Care

    Columbus, Ohio, 43210, United States

Conditions

Explore the condition pages connected to this study.