New drug tested to tame dangerous hormone overload
NCT ID NCT05307328
Summary
This study tested whether a drug called SPI-62 could safely help control the excess cortisol caused by certain tumors in adults with Cushing's syndrome. For 24 weeks, 26 participants received either the active drug or a placebo, with an option to continue on the drug long-term. The main goal was to see if the drug reduced a specific marker of the body's cortisol production.
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Contacts and locations
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Locations
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Carol Davila University of Medicine and Pharmacy
Bucharest, 050474, Romania
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Clinical Center of Endocrinology and Gerontology, University Hospital of Endocrinology, Medical University Sofia (USHATE)
Sofia, 1431, Bulgaria
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Comprehensive and Interventional Pain Management Llp
Henderson, Nevada, 89052, United States
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Mayo Clinic Cancer Center (MCCC) - Rochester
Rochester, Minnesota, 55905, United States
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Medical University of Plovdiv
Plovdiv, 4002, Bulgaria
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Medical University of Sofia
Sofia, 1431, Bulgaria
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Memorial Sloan-Kettering Cancer Center
New York, New York, 10065, United States
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Oregon Health & Science University (OHSU) - Northwest Pituitary Center
Portland, Oregon, 97239, United States
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Southwest General Healthcare Center
Fort Myers, Florida, 33907, United States
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St. Joseph's Hospital and Medical Center - Barrow Neurological Institute (BNI) - Pituitary Center
Phoenix, Arizona, 85013, United States
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University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, 15213, United States
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Washington University School of Medicine - Center for Advanced Medicine (CAM)
St Louis, Missouri, 63110, United States
Conditions
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