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Sleep aid from wheat germ? spermidine trial targets memory decline

NCT ID NCT07383311

First seen Feb 03, 2026 · Last updated May 20, 2026 · Updated 18 times

Summary

This study tests whether spermidine, a natural substance found in foods like wheat germ, can improve sleep quality and memory in older adults with mild cognitive impairment (MCI), a condition that raises dementia risk. 76 participants aged 55-70 will take spermidine or a placebo daily for 12 weeks. Sleep is measured with brain wave tests, and memory is checked with computer tasks. The goal is to see if improving sleep can help protect memory.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Neurology, University Medicine Greifswald

    RECRUITING

    Greifswald, Mecklenburg-Vorpommern, 17475, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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