Spinal injury sperm mystery: 18-Month study seeks answers
NCT ID NCT02144558
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study followed 35 men with spinal cord injuries over 18 months to see how their sperm quality changes and what factors might cause problems. Researchers measured sperm health, inflammation, and infections from ejaculates collected every 6 months. The goal is to find ways to preserve fertility and reduce the need for advanced fertility treatments.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could identify key risk factors that harm sperm quality in spinal cord injured men, leading to better long-term fertility care and possibly reducing the need for assisted reproduction.
- What could go wrong
- This is a small observational study with only 35 participants, so findings may not apply to all spinal cord injured men. It does not test any treatment, so it cannot directly improve fertility.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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35 people
The number who actually took part.
- Started
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Apr 2014
- Finished
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Apr 2018
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Male participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Spinal cord injured men aged between 18 and 60 years * Strict antegrade ejaculation obtained by masturbation or penil vibratory stimulation * Signature of an informed and written consent to participate to the study. Exclusion Criteria: * Total or partial retrograde ejaculation * Major patients protected * Men no affiliated with a french social security regime.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Assistance Publique-Hôpitaux de Paris, Cochin Hospital, Department of Biology of Reproduction
Paris, 75014, France