New depression pill SP-624 put to the test in large trial
NCT ID NCT06254612
First seen Nov 03, 2025 · Last updated May 23, 2026 · Updated 28 times
Summary
This study tests whether a new drug called SP-624 can safely reduce depression symptoms in adults with major depressive disorder. About 456 people will receive either SP-624 or a placebo (a dummy pill) to compare results. The main goal is to see if the drug improves mood and daily functioning better than placebo.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Accel Clinical
Lakeland, Florida, 33803, United States
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Accelerated Enrollment Solutions
Atlanta, Georgia, 30328, United States
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Alivation Research
Lincoln, Nebraska, 68526, United States
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Boston Clinical Trials
Boston, Massachusetts, 02131, United States
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CenExel HRI
Marlton, New Jersey, 08053, United States
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Center for Emotional Fitness
Cherry Hill, New Jersey, 08002, United States
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CiTrials
Riverside, California, 92506, United States
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Clinical Innovations
Bellflower, California, 90706, United States
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Clinical Neuroscience Solutions
Jacksonville, Florida, 32256, United States
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Clinical Neuroscience Solutions
Orlando, Florida, 32801, United States
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Clinical Neuroscience Solutions
Memphis, Tennessee, 38119, United States
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Coastal Carolina Research Center
North Charleston, South Carolina, 29405, United States
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Collaborative Neuroscience Research
Torrance, California, 90504, United States
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Core Clinical Research
Everett, Washington, 98201, United States
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DMI Research
Pinellas Park, Florida, 33782, United States
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Donald J. Garcia, Jr, MD, PA
Austin, Texas, 78737, United States
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Excell Research
Oceanside, California, 92056, United States
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Future Search Trials of Dallas
Dallas, Texas, 75231, United States
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Grayline Research Center
Wichita Falls, Texas, 76309, United States
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Haracec Clinical Research
El Paso, Texas, 79902, United States
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IMA Clinical Research
Phoenix, Arizona, 85012, United States
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IMA Clinical Research
Las Vegas, Nevada, 89102, United States
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IMA Clinical Research
Albuquerque, New Mexico, 87109, United States
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Integrative Clinical Trials
Brooklyn, New York, 11229, United States
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MCB Clinical Research Centers
Colorado Springs, Colorado, 80910, United States
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Magnolia Clinical Research
Cary, North Carolina, 27511, United States
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Midwest Clinical Research Center
Dayton, Ohio, 45417, United States
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Midwest Research Group
Saint Charles, Missouri, 63304, United States
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Neurobehavioral Medicine Group
Bloomfield Hills, Michigan, 48302, United States
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New Hope Clinical Research
Charlotte, North Carolina, 28211, United States
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Next Level Clinical Trials
West Covina, California, 91790, United States
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Noble Clinical Research
Tucson, Arizona, 85704, United States
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North Star Medical Research
Middleburg Heights, Ohio, 44130, United States
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Northwest Clinical Research Center
Bellevue, Washington, 98007, United States
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Pillar Clinical Research
Richardson, Texas, 75080, United States
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Pioneer Clinical Research
New York, New York, 10016, United States
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R and H Clinical Research
Stafford, Texas, 77477, United States
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Redbird Research
Las Vegas, Nevada, 89119, United States
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Revive Research Institute
Elgin, Illinois, 60123, United States
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SanRo Clinical Research Group
Bryant, Arkansas, 72022, United States
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Segal Trials
Lauderhill, Florida, 33319, United States
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Segal Trials - Miami Lakes
Miami Lakes, Florida, 33016, United States
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Summit Headlands
Portland, Oregon, 97210, United States
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Sun Valley Research Center
Imperial, California, 92251, United States
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Sunwise Clinical Research
Walnut Creek, California, 94596, United States
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Synergy San Diego
Lemon Grove, California, 91945, United States
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Tandem Clinical Research
Marrero, Louisiana, 70072, United States
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UNC Chapel Hill
Chapel Hill, North Carolina, 27599, United States
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Velocity Clinical Research
Meridian, Idaho, 83642, United States
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Velocity Clinical Research
Beachwood, Ohio, 44122, United States
Conditions
Explore the condition pages connected to this study.