Targeted switch may stall lung cancer in High-Risk patients
NCT ID NCT06333678
First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 28 times
Summary
This study looked at whether switching from the immunotherapy durvalumab to the targeted pill sotorasib could better control locally advanced non-small cell lung cancer in people with a KRAS G12C mutation. The switch was triggered when a blood test showed signs of remaining cancer after initial treatment. The trial enrolled 10 participants and compared how long the cancer stayed under control with the switch versus staying on durvalumab.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Memorial Sloan Kettering Basking Ridge (All Protocol Activities)
Basking Ridge, New Jersey, 07920, United States
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Memorial Sloan Kettering Bergen (All Protocol Activities)
Montvale, New Jersey, 07645, United States
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Memorial Sloan Kettering Cancer Center (All Protocol Activities)
New York, New York, 10065, United States
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Memorial Sloan Kettering Monmouth (All Protocol Activities)
Middletown, New Jersey, 07748, United States
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Memorial Sloan Kettering Nassau (All Protocol Activities)
Uniondale, New York, 11553, United States
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Memorial Sloan Kettering Suffolk - Commack (All Protocol Activities)
Commack, New York, 11725, United States
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Memorial Sloan Kettering Westchester (All Protocol Activities)
Harrison, New York, 10604, United States
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University of Miami (Data Collection Only)
Miami, Florida, 33136, United States
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University of Michigan (Data Collection Only)
Ann Arbor, Michigan, 48109, United States
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Vanderbilt University (Data Collection Only)
Nashville, Tennessee, 37232, United States
Conditions
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