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New combo therapy aims to halt multiple myeloma progression

NCT ID NCT01562405

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 30 times

Summary

This early-phase study tests a new drug called sotatercept (ACE-011) combined with two standard treatments (lenalidomide or pomalidomide plus dexamethasone) in 33 adults with multiple myeloma that has returned or not responded to prior therapy. The main goal is to find the safest dose of sotatercept and begin to see if the combination can shrink tumors and slow disease progression.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02215, United States

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Emory University

    Atlanta, Georgia, 30322, United States

  • Massachusetts General Hosptial

    Boston, Massachusetts, 02115, United States

Conditions

Explore the condition pages connected to this study.