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New hope for drug-resistant stomach cancer: sorafenib shows promise in early trial

NCT ID NCT00265798

First seen May 02, 2026 · Last updated Jun 08, 2026 · Updated 6 times

Summary

This study tested the drug sorafenib in 38 people with advanced gastrointestinal stromal tumor (GIST) that had stopped responding to two standard treatments, imatinib and sunitinib. Sorafenib works by blocking enzymes that help tumor cells grow and by cutting off blood supply to the tumor. The main goal was to see if the drug could shrink tumors or slow disease progression.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Central Illinois Hematology Oncology Center

    Springfield, Illinois, 62702, United States

  • City of Hope Comprehensive Cancer Center

    Duarte, California, 91010, United States

  • Decatur Memorial Hospital

    Decatur, Illinois, 62526, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • University of California Davis Comprehensive Cancer Center

    Sacramento, California, 95817, United States

  • University of Chicago Comprehensive Cancer Center

    Chicago, Illinois, 60637, United States

Conditions

The condition(s) this trial relates to.

gastrointestinal stromal tumor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.