New dosing strategy aims to reduce tumor lysis risk in CLL patients
NCT ID NCT06697184
First seen Nov 01, 2025 · Last updated May 18, 2026 · Updated 27 times
Summary
This study tests different ways to start and increase the dose of sonrotoclax in adults with chronic lymphocytic leukemia (CLL). The main goal is to see if these new dosing schedules lower the risk of tumor lysis syndrome, a serious side effect. About 56 participants will be enrolled, and researchers will monitor for side effects and safety. This is an early-stage trial focused on safety, not a cure.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Blacktown Cancer and Haematology Centre
Blacktown, New South Wales, NSW 2148, Australia
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Cabrini Hospital Malvern
Malvern East, Victoria, VIC 3144, Australia
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Chu Dijon
Dijon, 21000, France
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Chu Montpellier Hopital Saint Eloi
Montpellier, 34090, France
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Dana Farber Cancer Institute
Boston, Massachusetts, 02215-5418, United States
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Fort Wayne Medical Oncology and Hematology
Fort Wayne, Indiana, 46804, United States
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Fred Hutchinson Cancer Research Center
Seattle, Washington, 98109-4433, United States
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Genesiscare St Andrews
Adelaide, South Australia, SA 5000, Australia
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Iuct Oncopole
Toulouse, 31100, France
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Linear Clinical Research
Nedlands, Western Australia, WA 6009, Australia
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Moffitt Cancer Center
Tampa, Florida, 33612-9496, United States
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Queen Elizabeth Hospital
Birmingham, B15 2TH, United Kingdom
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Rockingham Hospital
Cooloongup, Western Australia, WA 6168, Australia
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St Jamess University Hospital
Leeds, LS9 7TF, United Kingdom
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The Alfred Hospital
Melbourne, Victoria, VIC 3004, Australia
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The University of Kansas Cancer Center
Westwood, Kansas, 66205-2003, United States
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Washington University School of Medicine
St Louis, Missouri, 63110-1010, United States
Conditions
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