Scientists test gentler start for promising leukemia drug

NCT ID NCT06697184

Summary

This study is testing new, potentially safer ways to start treatment with an experimental drug called sonrotoclax for adults with chronic lymphocytic leukemia (CLL). The goal is to find the best schedule for slowly increasing the drug dose at the beginning of treatment to reduce side effects, especially a serious one called tumor lysis syndrome. About 56 participants worldwide will help researchers determine which starting schedule is safest.

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Contacts and locations

Locations

  • Blacktown Cancer and Haematology Centre

    Blacktown, New South Wales, NSW 2148, Australia

  • Cabrini Hospital Malvern

    Malvern East, Victoria, VIC 3144, Australia

  • Chu Dijon

    Dijon, 21000, France

  • Chu Montpellier Hopital Saint Eloi

    Montpellier, 34090, France

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215-5418, United States

  • Fort Wayne Medical Oncology and Hematology

    Fort Wayne, Indiana, 46804, United States

  • Fred Hutchinson Cancer Research Center

    Seattle, Washington, 98109-4433, United States

  • Genesiscare St Andrews

    Adelaide, South Australia, SA 5000, Australia

  • Iuct Oncopole

    Toulouse, 31100, France

  • Linear Clinical Research

    Nedlands, Western Australia, WA 6009, Australia

  • Moffitt Cancer Center

    Tampa, Florida, 33612-9496, United States

  • Queen Elizabeth Hospital

    Birmingham, B15 2TH, United Kingdom

  • Rockingham Hospital

    Cooloongup, Western Australia, WA 6168, Australia

  • St Jamess University Hospital

    Leeds, LS9 7TF, United Kingdom

  • The Alfred Hospital

    Melbourne, Victoria, VIC 3004, Australia

  • The University of Kansas Cancer Center

    Westwood, Kansas, 66205-2003, United States

  • Washington University School of Medicine

    St Louis, Missouri, 63110-1010, United States

Conditions

Explore the condition pages connected to this study.