New drug combo shows promise against rare liver virus
NCT ID NCT05461170
First seen Nov 01, 2025 · Last updated Jun 19, 2026 · Updated 37 times
Summary
This study tests two experimental drugs, VIR-2218 and VIR-3434, in 95 adults with chronic hepatitis D, a serious liver infection. The goal is to see if the drugs can lower the virus to undetectable levels and improve liver function. Participants must already be on standard hepatitis B therapy. The study is active but not recruiting new participants.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Investigative Site
Sofia, 1407, Bulgaria
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Investigative Site
Sofia, 1431, Bulgaria
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Investigative Site
Stara Zagora, 6003, Bulgaria
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Investigative Site
Clichy, 92110, France
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Investigative Site
Pessac, 33600, France
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Investigative Site
Rennes, 35000, France
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Investigative Site
Toulouse, 31000, France
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Investigative Site
Frankfurt, 60596, Germany
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Investigative Site
Hanover, 30625, Germany
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Investigative Site
Tübingen, 72076, Germany
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Investigative Site
Milan, 20122, Italy
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Investigative Site
Pisa, 56124, Italy
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Investigative Site
Chisinau, MD-2025, Moldova
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Investigative Site
Rotterdam, 3015 GD, Netherlands
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Investigative Site
Auckland, 1010, New Zealand
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Investigative Site
Bucharest, 021105, Romania
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Investigative Site
Birmingham, B15 2TT, United Kingdom
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Investigative Site
London, E1 1RF, United Kingdom
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Investigative Site
London, SE5 9RS, United Kingdom
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Investigative Site
Manchester, M8 5RB, United Kingdom
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.