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Buddy system tested to keep HIV patients healthy and in care

NCT ID NCT05723653

Disease control Sponsor: University of Chicago Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether having a trusted friend or family member (a Support Confidant) can help people with HIV keep their medical appointments and lower their virus levels. Researchers will enroll 900 people aged 18-49 in Chicago and Alabama who have missed visits or had unsuppressed virus. The program includes choosing a support person, a face-to-face meeting with a case manager, and quarterly check-ins by text or phone.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Social Network Support Intervention (behavioural program involving a Support Confidant and case manager sessions)
What this could lead to
If it works, this could offer a low-cost, community-based way to help people with HIV stay in care and keep the virus under control.
What could go wrong
This is a behavioural intervention, not a drug, so results may vary. It is still recruiting and the effect on viral suppression is not yet proven.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 900 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2023

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 49 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria for Index Participants: * Aged 18-49 years old, inclusive * Speak English * Own a cell phone not shared with anyone else * Have missed at least one HIV care scheduled visit or have not been virally suppressed in the past 24 months. * Resides in Chicagoland, Illinois or Alabama Exclusion Criteria for Index Men: * If a participant fails to meet all inclusion criteria Inclusion Criteria for Support Confidants: * Index agrees to engage the Support Confidant * Age 18 years or older * Speaks English * Owns a cell phone not shared with others * Is not a romantic/sexual partner of the Index participant Exclusion Criteria: * Romantic/Sexual partners of Index participant * Relationship strain or abuse present in Index-Support Confidant relationship

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Conditions

The condition(s) this trial relates to.

HIV infectious disease HIV Seropositivity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV seropositivity

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    7 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Birmingham AIDS Outreach

    RECRUITING

    Birmingham, Alabama, 35233, United States

  • Chicago Center for HIV Elimination

    RECRUITING

    Chicago, Illinois, 60637, United States

  • Crown Family School of Social Work, Policy, and Practice at the University of Chicago

    NOT_YET_RECRUITING

    Chicago, Illinois, 60637, United States

  • Howard Brown Health

    RECRUITING

    Chicago, Illinois, 60613, United States

  • Thrive Alabama

    RECRUITING

    Huntsville, Alabama, 65801, United States

  • Tulane University

    NOT_YET_RECRUITING

    New Orleans, Louisiana, 70118, United States

  • University of Alabama at Birmingham 1917 Clinic

    NOT_YET_RECRUITING

    Birmingham, Alabama, 35205, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.