New test may uncover hidden social struggles in huntington disease
NCT ID NCT07253038
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how Huntington disease affects social skills, like understanding others' feelings and intentions. Researchers will test a new tool called DMASC-MC in 40 adults with early Huntington disease and compare results to healthy volunteers. The goal is to find better ways to detect social difficulties, which could help patients and families get the right support.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2025
- Expected to finish
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Sep 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Recruitment of participants will be made at the HD clinic in Lund, Sweden and through ethical review board-approved advertisment material posted at social media platforms and websites hosted by the Huntingtoncenter at Lund and the Swedish patient organization Riksförbundet för Huntingtons sjukdom (RHS) as well as YTAN.
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Inclusion criteria for persons with HD 1. Clinical diagnosis of HD 2. CAG repeat: 40 and more Inclusion criteria for control group 1\. No heritage of HD or negative pre-symptomatic HD gene test Exclusion Criteria: Participants in both groups are excluded from the study if any of the following criteria apply: 1. Dementia or MOCA\<19, The Mini Mental State Examination (MMSE) \<19 2. Other neurological disorders 3. Ongoing psychosis 4. Ongoing alcohol/drug addiction 5. Other native language than Swedish 6. Severe problems with vision and hearing
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Skane University Hospital, Region Skane
RECRUITINGLund, 22184, Sweden
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a single molecule quiet the genetic chaos behind three brain diseases?
- Can a genetic 'Patch' fix Huntington's disease? lab test aims to find out
- Could a brain disease change behavior years before diagnosis?
- Scientists decode gait signatures to spot brain diseases
- Can a One-Page guide spark better End-of-Life talks for dementia patients?