Can a Plant-Based pill help HIV patients quit smoking and drinking?
NCT ID NCT06790342
First seen Jan 11, 2026 · Last updated Jun 21, 2026 · Updated 29 times
Summary
This study in Nairobi, Kenya, will test whether a drug called cytisine, combined with counseling, can help 300 people with HIV quit smoking and reduce heavy drinking. Participants will receive either cytisine or a placebo, plus either intensive counseling or standard advice. The goal is to see if this combination improves health outcomes in a resource-limited setting.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Mathari National Teaching and Referral Hospital
Nairobi, Kenya
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Riruta Health Centre
Nairobi, Kenya
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Cytisine (a plant-based drug to help quit smoking and reduce alcohol use)
What this could lead to
If successful, this could provide an effective, low-cost treatment option for people with HIV who smoke and drink heavily, potentially reducing their risk of serious health problems.
What could go wrong
This is a Phase 3 trial, but it's still early to know if cytisine works better than standard advice. The results may not apply to all populations, and side effects from cytisine are possible.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.